Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.

Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.

Chemokines promote T cell migration by transmitting signals that induce T cell polarization and integrin activation and adhesion. Mst1 kinase is a key signal mediator required for both of these processes; however, its molecular mechanism remains unclear. Here, we present a mouse model in which Mst1...

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Bibliographic Details
Main Authors: Xiaolu Xu, Emily R Jaeger, Xinxin Wang, Erica Lagler-Ferrez, Serge Batalov, Nancy L Mathis, Tim Wiltshire, John R Walker, Michael P Cooke, Karsten Sauer, Yina H Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136924?pdf=render

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http://europepmc.org/articles/PMC4136924?pdf=render

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