Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.
Chemokines promote T cell migration by transmitting signals that induce T cell polarization and integrin activation and adhesion. Mst1 kinase is a key signal mediator required for both of these processes; however, its molecular mechanism remains unclear. Here, we present a mouse model in which Mst1...
Main Authors: | Xiaolu Xu, Emily R Jaeger, Xinxin Wang, Erica Lagler-Ferrez, Serge Batalov, Nancy L Mathis, Tim Wiltshire, John R Walker, Michael P Cooke, Karsten Sauer, Yina H Huang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4136924?pdf=render |
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