Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma

Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma

Neoantigens present unique and specific targets for personalized cancer immunotherapy strategies. Given the low mutational burden yet immunotherapy responsiveness of malignant mesothelioma (MM) when compared to other carcinogen-induced malignancies, identifying candidate neoantigens and T cells that...

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Bibliographic Details
Main Authors: Sophie Sneddon, Craig M. Rive, Shaokang Ma, Ian M. Dick, Richard J. N. Allcock, Scott D. Brown, Robert A. Holt, Mark Watson, Shay Leary, Y. C. Gary Lee, Bruce W. S. Robinson, Jenette Creaney
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
malignant mesothelioma
neoantigen
pleural effusion
tumor-immune interface
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1684713

Internet

http://dx.doi.org/10.1080/2162402X.2019.1684713

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