STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia

STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia

Abstract Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly described constitutive Ca2+ entry (CE) pathway is less...

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Bibliographic Details
Main Authors: Marjolaine Debant, Miguel Burgos, Patrice Hemon, Paul Buscaglia, Tinhinane Fali, Sarra Melayah, Nelig Le Goux, Christophe Vandier, Marie Potier-Cartereau, Jacques-Olivier Pers, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Olivier Mignen, Yves Renaudineau
Format: Article
Language:English
Published: BMJ Publishing Group 2019-04-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
CLL
STIM1
Constitutive Ca2+ entry
Disease outcome
Online Access:http://link.springer.com/article/10.1186/s40425-019-0591-3

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http://link.springer.com/article/10.1186/s40425-019-0591-3

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