Effects of temperature and wavelength choice on in-situ dissolution test of Cimetidine tablets

The effects of temperature and wavelength choice on in-situ dissolution test instrument of Cimetidine were studied. Absorbance (A)<1.0 is required when using a fiber-optic dissolution test system. The detection wavelength of λmax (218 nm) was replaced by 244 nm to carry out this test. The abso...

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Bibliographic Details
Main Authors: Xin-Xia Li, Yan Wang, Ping-Ping Xu, Qi-Zhou Zhang, Kun Nie, Xu Hu, Bin Kong, Li Li, Jian Chen
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177912000718