The Role of RNA Binding Proteins for Local mRNA Translation: Implications in Neurological Disorders

As neurons are one of the most highly polarized cells in our body, they require sophisticated cellular mechanisms to maintain protein homeostasis in their subcellular compartments such as axons and dendrites. When neuronal protein homeostasis is disturbed due to genetic mutations or deletions, this...

Full description

Bibliographic Details
Main Authors: Maximilian Paul Thelen, Min Jeong Kye
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
SMA
ALS
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00161/full