SERCA2 regulates non-CF and CF airway epithelial cell response to ozone.

Calcium mobilization can regulate a wide range of essential functions of respiratory epithelium, including ion transport, ciliary beat frequency, and secretion of mucus, all of which are modified in cystic fibrosis (CF). SERCA2, an important controller of calcium signaling, is deficient in CF epithe...

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Bibliographic Details
Main Authors: Shama Ahmad, David P Nichols, Matthew Strand, Raymond C Rancourt, Scott H Randell, Carl W White, Aftab Ahmad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3214057?pdf=render