Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study

Bibliographic Details
Main Authors: T Kendrick, J Chatwin, C Dowrick, A Tylee, R Morriss, R Peveler, M Leese, P McCrone, T Harris, M Moore, R Byng, G Brown, S Barthel, H Mander, A Ring, V Kelly, V Wallace, M Gabbay, T Craig, A Mann
Format: Article
Language:English
Published: NIHR Journals Library 2009-04-01
Series:Health Technology Assessment
Online Access:https://doi.org/10.3310/hta13220
id doaj-a5d5c5e526344572b6d598960fdf357b
record_format Article
spelling doaj-a5d5c5e526344572b6d598960fdf357b2020-11-25T00:15:24ZengNIHR Journals LibraryHealth Technology Assessment1366-52782009-04-01132210.3310/hta13220Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) studyT Kendrick0J ChatwinC DowrickA TyleeR MorrissR PevelerM LeeseP McCroneT HarrisM MooreR ByngG BrownS BarthelH ManderA RingV KellyV WallaceM GabbayT CraigA MannPrimary Medical Care, Aldermoor Health Centre, University of Southampton, UKhttps://doi.org/10.3310/hta13220
collection DOAJ
language English
format Article
sources DOAJ
author T Kendrick
J Chatwin
C Dowrick
A Tylee
R Morriss
R Peveler
M Leese
P McCrone
T Harris
M Moore
R Byng
G Brown
S Barthel
H Mander
A Ring
V Kelly
V Wallace
M Gabbay
T Craig
A Mann
spellingShingle T Kendrick
J Chatwin
C Dowrick
A Tylee
R Morriss
R Peveler
M Leese
P McCrone
T Harris
M Moore
R Byng
G Brown
S Barthel
H Mander
A Ring
V Kelly
V Wallace
M Gabbay
T Craig
A Mann
Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study
Health Technology Assessment
author_facet T Kendrick
J Chatwin
C Dowrick
A Tylee
R Morriss
R Peveler
M Leese
P McCrone
T Harris
M Moore
R Byng
G Brown
S Barthel
H Mander
A Ring
V Kelly
V Wallace
M Gabbay
T Craig
A Mann
author_sort T Kendrick
title Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study
title_short Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study
title_full Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study
title_fullStr Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study
title_full_unstemmed Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study
title_sort randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the thread (threshold for antidepressant response) study
publisher NIHR Journals Library
series Health Technology Assessment
issn 1366-5278
publishDate 2009-04-01
url https://doi.org/10.3310/hta13220
work_keys_str_mv AT tkendrick randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT jchatwin randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT cdowrick randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT atylee randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT rmorriss randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT rpeveler randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT mleese randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT pmccrone randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT tharris randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT mmoore randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT rbyng randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT gbrown randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT sbarthel randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT hmander randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT aring randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT vkelly randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT vwallace randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT mgabbay randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT tcraig randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
AT amann randomisedcontrolledtrialtodeterminetheclinicaleffectivenessandcosteffectivenessofselectiveserotoninreuptakeinhibitorsplussupportivecareversussupportivecarealoneformildtomoderatedepressionwithsomaticsymptomsinprimarycarethethreadthresholdforantidepressant
_version_ 1725387097055952896