Conformational changes of blood ACE in chronic uremia.

BACKGROUND: The pattern of binding of monoclonal antibodies (mAbs) to 16 epitopes on human angiotensin I-converting enzyme (ACE) comprise a conformational ACE fingerprint and is a sensitive marker of subtle protein conformational changes. HYPOTHESIS: Toxic substances in the blood of patients with ur...

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Bibliographic Details
Main Authors: Maxim N Petrov, Valery Y Shilo, Alexandr V Tarasov, David E Schwartz, Joe G N Garcia, Olga A Kost, Sergei M Danilov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500299?pdf=render