Postnatal Arx transcriptional activity regulates functional properties of PV interneurons

Postnatal Arx transcriptional activity regulates functional properties of PV interneurons

Summary: The transcription factor Aristaless-related X-linked gene (Arx) is a monogenic factor in early onset epileptic encephalopathies (EOEEs) and a fundamental regulator of early stages of brain development. However, Arx expression persists in mature GABAergic neurons with an unknown role. To add...

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Bibliographic Details
Main Authors: Donald J. Joseph, Markus Von Deimling, Yuiko Hasegawa, Ana G. Cristancho, Rebecca C. Ahrens-Nicklas, Stephanie L. Rogers, Rashmi Risbud, Almedia J. McCoy, Eric D. Marsh
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Behavioral Neuroscience
Molecular Neuroscience
Cellular Neuroscience
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311962

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http://www.sciencedirect.com/science/article/pii/S2589004220311962

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