Small interfering RNA targeting PGC-1α inhibits VEGF expression and tube formation in human retinal vascular endothelial cells

<b>AIM:</b>To determine whether small interfering RNA (siRNA) of PGC-1α could inhibit vascular endothelial growth factor (VEGF) expression and tube formation in human retinal vascular endothelial cells (hRVECs).<b>METHODS:</b>hRVECs transfected with peroxisome proliferator-ac...

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Bibliographic Details
Main Authors: Jian Jiang, Lu Zhang, Xiao-Bo Xia
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-10-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2015/5/20150505.pdf