Multidrug Resistance and Cancer Stem Cells in Neuroblastoma and Hepatoblastoma

Chemotherapy is one of the major modalities in treating cancers. However, its effectiveness is limited by the acquisition of multidrug resistance (MDR). Several mechanisms could explain the up-regulation of MDR genes/proteins in cancer after chemotherapy. It is known that cancer stem cells (CSCs) pl...

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Bibliographic Details
Main Authors: Anna Alisi, William C. Cho, Franco Locatelli, Doriana Fruci
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/12/24706