Inhibition of Growth and Gene Expression by PNA-peptide Conjugates in Streptococcus pyogenes

While Streptococcus pyogenes is consistently susceptible toward penicillin, therapeutic failure of penicillin treatment has been reported repeatedly and a considerable number of patients exhibit allergic reactions to this substance. At the same time, streptococcal resistance to alternative antibioti...

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Bibliographic Details
Main Authors: Nadja Patenge, Roberto Pappesch, Franziska Krawack, Claudia Walda, Mobarak Abu Mraheil, Anette Jacob, Torsten Hain, Bernd Kreikemeyer
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
PNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116301937