Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets

Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets

Common variable immunodeficiency (CVID) is increasingly recognized for its association with autoimmune and inflammatory complications. Despite recent advances in immunophenotypic and genetic discovery, clinical care of CVID remains limited by our inability to accurately model risk for non-infectious...

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Bibliographic Details
Main Authors: Jocelyn R. Farmer, Mei-Sing Ong, Sara Barmettler, Lael M. Yonker, Ramsay Fuleihan, Kathleen E. Sullivan, Charlotte Cunningham-Rundles, The USIDNET Consortium, Jolan E. Walter
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
common variable immunodeficiency
non-infectious complications
endotypes
atopy
autoimmunity
lymphoproliferation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01740/full

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.01740/full

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