A model for prediction of cisplatin induced nephrotoxicity by kidney weight in experimental rats

A model for prediction of cisplatin induced nephrotoxicity by kidney weight in experimental rats

Background: Cisplatin (cis-diamminedichloroplatinum II; CP) is used widely as an antitumor drug in clinics, but is accompanied with renal toxicity. Cisplatin induced nephrotoxicity consists of change in kidney weight, histological changes in kidney and increase in serum creatinine (Cr) and blood ure...

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Bibliographic Details
Main Authors: Mehdi Nematbakhsh, Farzaneh Ashrafi, Hamid Nasri, Ardeshir Talebi, Zahra Pezeshki, Fatemeh Eshraghi, Maryam Haghighi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Cisplatin
kidney weight
nephrotoxicity
pathology
rat
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2013;volume=18;issue=5;spage=370;epage=373;aulast=Nematbakhsh

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http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2013;volume=18;issue=5;spage=370;epage=373;aulast=Nematbakhsh

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