Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells
Pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, is one of the most lethal human diseases. PDAC is now the fourth leading cause of cancer mortality in both men and women and deaths due to PDAC are projected to increase dramatically. Novel targets and agents for ch...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-09-01
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Series: | Frontiers in Physiology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00357/full |