BMS-536924, an ATP-competitive IGF-1R/IR inhibitor, decreases viability and migration of temozolomide-resistant glioma cells in vitro and suppresses tumor growth in vivo

Qiao ZhouSchool of Public Affairs, University of Science and Technology of China, Hefei, Anhui, People’s Republic of ChinaAbstract: Glioma is the most common type of primary brain tumor. Despite the combination of surgery, chemotherapy, and radiotherapy, the median survival durat...

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Bibliographic Details
Main Author: Zhou Q
Format: Article
Language:English
Published: Dove Medical Press 2015-04-01
Series:OncoTargets and Therapy
Online Access:http://www.dovepress.com/bms-536924-an-atp-competitive-igf-1rir-inhibitor-decreases-viability-a-peer-reviewed-article-OTT