Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease

Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease

Abstract Background Network alterations underlying neurodegenerative diseases often precede symptoms and functional deficits. Thus, their early identification is central for improved prognosis. In Huntington’s disease (HD), the cortico-striatal networks, involved in motor function processing, are th...

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Bibliographic Details
Main Authors: S. Fernández-García, J. G. Orlandi, G. A. García-Díaz Barriga, M. J. Rodríguez, M. Masana, J. Soriano, J. Alberch
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Biology
Subjects:
Network
Striatum
Calcium imaging
Neuronal activity
Huntington’s disease
Online Access:http://link.springer.com/article/10.1186/s12915-020-00794-4

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http://link.springer.com/article/10.1186/s12915-020-00794-4

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