Prokineticin receptor 2 affects GnRH3 neuron ontogeny but not fertility in zebrafish

Abstract Prokineticin receptors (PROKR1 and PROKR2) are G protein-coupled receptors which control human central and peripheral reproductive processes. Importantly, allelic variants of PROKR2 in humans are associated with altered migration of GnRH neurons, resulting in congenital hypogonadotropic hyp...

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Bibliographic Details
Main Authors: Ivan Bassi, Francesca Luzzani, Federica Marelli, Valeria Vezzoli, Ludovica Cotellessa, David A. Prober, Luca Persani, Yoav Gothilf, Marco Bonomi
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-64077-2