Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges

Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges

The immune cytokine tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has attracted rapidly evolving attention as a cancer treatment modality because of its competence to selectively eliminate tumor cells without instigating toxicity in vivo. TRAIL has revealed encouraging promise in p...

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Bibliographic Details
Main Authors: Ehsan Razeghian, Wanich Suksatan, Heshu Sulaiman Rahman, Dmitry O. Bokov, Walid Kamal Abdelbasset, Ali Hassanzadeh, Faroogh Marofi, Mahboubeh Yazdanifar, Mostafa Jarahian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
tumor necrosis factor-related apoptosis-inducing ligand
mesenchymal stem/stromal cells
resistance
nanoparticles
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.699746/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.699746/full

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