Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis.

Bone morphogenetic protein (BMP) family members, including BMP2, BMP4, and BMP7, are expressed throughout limb development. BMPs have been implicated in early limb patterning as well as in the process of skeletogenesis. However, due to complications associated with early embryonic lethality, particu...

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Bibliographic Details
Main Authors: Amitabha Bandyopadhyay, Kunikazu Tsuji, Karen Cox, Brian D Harfe, Vicki Rosen, Clifford J Tabin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1713256?pdf=render