Trem-2 Promotes Emergence of Restorative Macrophages and Endothelial Cells During Recovery From Hepatic Tissue Damage

Trem-2 Promotes Emergence of Restorative Macrophages and Endothelial Cells During Recovery From Hepatic Tissue Damage

Macrophages are pivotal in mounting liver inflammatory and tissue repair responses upon hepatic injury, showing remarkable functional plasticity. The molecular mechanisms determining macrophage transition from inflammatory to restorative phenotypes in the damaged liver remain unclear. Using mouse mo...

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Bibliographic Details
Main Authors: Inês Coelho, Nádia Duarte, André Barros, Maria Paula Macedo, Carlos Penha-Gonçalves
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
triggering receptor expressed on myeloid cells 2
macrophages
tissue repair and organ regeneration
inflammation
carbon tetrachloride 4
acetaminophen (paracetamol)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.616044/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.616044/full

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