A Re-Appraisal of Pathogenic Mechanisms Bridging Wet and Dry Age-Related Macular Degeneration Leads to Reconsider a Role for Phytochemicals

A Re-Appraisal of Pathogenic Mechanisms Bridging Wet and Dry Age-Related Macular Degeneration Leads to Reconsider a Role for Phytochemicals

Which pathogenic mechanisms underlie age-related macular degeneration (AMD)? Are they different for dry and wet variants, or do they stem from common metabolic alterations? Where shall we look for altered metabolism? Is it the inner choroid, or is it rather the choroid–retinal border? Again, since c...

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Bibliographic Details
Main Authors: Roberto Pinelli, Francesca Biagioni, Fiona Limanaqi, Miorica Bertelli, Elena Scaffidi, Maico Polzella, Carla Letizia Busceti, Francesco Fornai
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy
proteasome
immunoproteasome
oxidative stress
inflammation
retinal pigment epithelium
Online Access:https://www.mdpi.com/1422-0067/21/15/5563

Internet

https://www.mdpi.com/1422-0067/21/15/5563

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