Subcellular Localization and Mitotic Interactome Analyses Identify SIRT4 as a Centrosomally Localized and Microtubule Associated Protein

Subcellular Localization and Mitotic Interactome Analyses Identify SIRT4 as a Centrosomally Localized and Microtubule Associated Protein

The stress-inducible and senescence-associated tumor suppressor SIRT4, a member of the family of mitochondrial sirtuins (SIRT3, SIRT4, and SIRT5), regulates bioenergetics and metabolism via NAD<sup>+</sup>-dependent enzymatic activities. Next to the known mitochondrial location, we found...

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Bibliographic Details
Main Authors: Laura Bergmann, Alexander Lang, Christoph Bross, Simone Altinoluk-Hambüchen, Iris Fey, Nina Overbeck, Anja Stefanski, Constanze Wiek, Andreas Kefalas, Patrick Verhülsdonk, Christian Mielke, Dennis Sohn, Kai Stühler, Helmut Hanenberg, Reiner U. Jänicke, Jürgen Scheller, Andreas S. Reichert, Mohammad Reza Ahmadian, Roland P. Piekorz
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
sirtuin
SIRT4
interactome
centrosome
mitosis
HDAC6
Online Access:https://www.mdpi.com/2073-4409/9/9/1950

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https://www.mdpi.com/2073-4409/9/9/1950

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