The Inhibitory Effect of (−)-Epigallocatechin-3-Gallate on Breast Cancer Progression via Reducing <i>SCUBE2</i> Methylation and DNMT Activity

The Inhibitory Effect of (−)-Epigallocatechin-3-Gallate on Breast Cancer Progression via Reducing <i>SCUBE2</i> Methylation and DNMT Activity

Epigenetic modifications are important mechanisms responsible for cancer progression. Accumulating data suggest that (&#8722;)-epigallocatechin-3-gallate (EGCG), the most abundant catechin of green tea, may hamper carcinogenesis by targeting epigenetic alterations. We found that signal peptide-C...

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Bibliographic Details
Main Authors: Jie Sheng, Weilin Shi, Hui Guo, Wenlin Long, Yuxin Wang, Jiangfa Qi, Jinbiao Liu, Yao Xu
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
EGCG
<i>SCUBE2</i> gene
methylation
migration and invasion
breast cancer
Online Access:https://www.mdpi.com/1420-3049/24/16/2899

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https://www.mdpi.com/1420-3049/24/16/2899

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