Angiopoietin-2 silence alleviates lipopolysaccharide-induced inflammation, barrier dysfunction and endoplasmic reticulum stress of intestinal epithelial cells by blocking Notch signaling pathway

Angiopoietin-2 silence alleviates lipopolysaccharide-induced inflammation, barrier dysfunction and endoplasmic reticulum stress of intestinal epithelial cells by blocking Notch signaling pathway

Necrotizing enterocolitis, a devastating gastrointestinal disease with high mortality, poses great threats to global health. Therefore, we conducted this study to explore the role of ANGPT2, as well as the potential mechanism, in necrotizing enterocolitis. IEC-6 cells were stimulated with lipopolysa...

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Bibliographic Details
Main Authors: Liying Dai, Shuangshuang Jie, Shaohua Bi, Qing Qing, Jun Chen, Le Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Bioengineered
Subjects:
necrotizing enterocolitis
angpt2
inflammation response
barrier dysfunction
endoplasmic reticulum stress
notch signaling pathway
Online Access:http://dx.doi.org/10.1080/21655979.2021.1985341

Internet

http://dx.doi.org/10.1080/21655979.2021.1985341

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