Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammation

Abstract The severity and course of inflammatory processes differ between women and men, but the biochemical mechanisms underlying these sex differences are elusive. Prostaglandins (PG) and leukotrienes (LT) are lipid mediators linked to inflammation. We demonstrated superior LT biosynthesis in huma...

Full description

Bibliographic Details
Main Authors: Simona Pace, Antonietta Rossi, Verena Krauth, Friederike Dehm, Fabiana Troisi, Rossella Bilancia, Christina Weinigel, Silke Rummler, Oliver Werz, Lidia Sautebin
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03696-8