PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation

PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation

Mechanical-loading and unloading can modify osteoblast functioning. Ca<sup>2+</sup> signaling is one of the earliest events in osteoblasts to induce a mechanical stimulus, thereby demonstrating the importance of the underlying mechanical sensors for the sensation. Here, we examined the m...

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Bibliographic Details
Main Authors: Maki Yoneda, Hiroka Suzuki, Noriyuki Hatano, Sayumi Nakano, Yukiko Muraki, Ken Miyazawa, Shigemi Goto, Katsuhiko Muraki
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
trpv4
piezo1
yoda1
mc3t3-e1 cells
mechanical stimulation
cell proliferation
Online Access:https://www.mdpi.com/1422-0067/20/19/4960

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https://www.mdpi.com/1422-0067/20/19/4960

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