Insights Into the Role and Potential of Schwann Cells for Peripheral Nerve Repair From Studies of Development and Injury

Insights Into the Role and Potential of Schwann Cells for Peripheral Nerve Repair From Studies of Development and Injury

Peripheral nerve injuries arising from trauma or disease can lead to sensory and motor deficits and neuropathic pain. Despite the purported ability of the peripheral nerve to self-repair, lifelong disability is common. New molecular and cellular insights have begun to reveal why the peripheral nerve...

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Bibliographic Details
Main Authors: Anjali Balakrishnan, Lauren Belfiore, Tak-Ho Chu, Taylor Fleming, Rajiv Midha, Jeff Biernaskie, Carol Schuurmans
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
repair Schwann cells
peripheral nerve injury
transcriptional regulators
directed reprogramming
nerve repair
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.608442/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2020.608442/full

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