A naturally occurring carotenoid, lutein, reduces PDGF and H<sub>2</sub>O<sub>2 </sub>signaling and compromised migration in cultured vascular smooth muscle cells

A naturally occurring carotenoid, lutein, reduces PDGF and H<sub>2</sub>O<sub>2 </sub>signaling and compromised migration in cultured vascular smooth muscle cells

<p>Abstract</p> <p>Background</p> <p>Platelet-derived growth factor (PDGF) is a potent stimulator of growth and motility of vascular smooth muscle cells (VSMCs). Abnormalities of PDGF/PDGF receptor (PDGFR) are thought to contribute to vascular diseases and malignancy. W...

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Bibliographic Details
Main Authors: Lo Huey-Ming, Tsai Yih-Jeng, Du Wen-Yuan, Tsou Chih-Jen, Wu Wen-Bin
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Journal of Biomedical Science
Subjects:
binding
carotenoid
lutein
migration
oxidative stress
signaling
Online Access:http://www.jbiomedsci.com/content/19/1/18

Internet

http://www.jbiomedsci.com/content/19/1/18

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