Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem (iPS) Cells Suppress or Activate T Cells via Costimulatory Signals

Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem (iPS) Cells Suppress or Activate T Cells via Costimulatory Signals

Human retinal pigment epithelial (RPE) cells derived from induced pluripotent stem (iPS) cells have immunosuppressive properties. However, RPE cells are also known as immunogenic cells, and they have major histocompatibility complex expression and produce inflammatory proteins, and thus experience i...

Full description

Bibliographic Details
Main Authors: Sunao Sugita, Yoko Futatsugi, Masaaki Ishida, Ayaka Edo, Masayo Takahashi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
iPS cells
retinal pigment epithelial cells
uveitis
suppression
stimulation
costimulatory molecules
Online Access:https://www.mdpi.com/1422-0067/21/18/6507

Internet

https://www.mdpi.com/1422-0067/21/18/6507

Similar Items