The Role of Alloresponsive Ly49 NK Cells in Rat Islet Allograft Failure in the Presence and Absence of Cytomegalovirus

There are still many factors to discover to explain the low success rates of islet allografts. In this study, we demonstrate that specific subpopulations of alloreactive NK cells may be involved in the failure of islet allografts. By performing allotransplantation in rats ( n = 13), we observed peri...

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Bibliographic Details
Main Authors: Maaike J. Smelt, Marijke M. Faas, Bart J. De Haan, Aalzen De Haan, John T. Vaage, Paul De Vos Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2014-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368913X670930