Development of rotational intraperitoneal pressurized aerosol chemotherapy to enhance drug delivery into the peritoneum

Development of rotational intraperitoneal pressurized aerosol chemotherapy to enhance drug delivery into the peritoneum

This study aims to evaluate the drug distribution, tissue concentrations, penetration depth, pharmacokinetic properties, and toxicities after rotational intraperitoneal pressurized aerosol chemotherapy (RIPAC) in pigs. Because relevant medical devices have not been introduced, we developed our proto...

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Bibliographic Details
Main Authors: Soo Jin Park, Eun Ji Lee, Hee Su Lee, Junsik Kim, Sunwoo Park, Jiyeon Ham, Jaehee Mun, Haerin Paik, Hyunji Lim, Aeran Seol, Ga Won Yim, Seung-Hyuk Shim, Beong-Cheol Kang, Suk Joon Chang, Whasun Lim, Gwonhwa Song, Jae-Weon Kim, Nara Lee, Ji Won Park, Jung Chan Lee, Hee Seung Kim, On behalf of the KoRIA* trial group
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
intraperitoneal chemotherapy
doxorubicin
pharmacokinetics
drug delivery
peritoneal metastasis
Online Access:http://dx.doi.org/10.1080/10717544.2021.1937382

Internet

http://dx.doi.org/10.1080/10717544.2021.1937382

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