The multifunctional Ca²⁺/calmodulin-dependent kinase IIδ (CaMKIIδ) regulates arteriogenesis in a mouse model of flow-mediated remodeling.

The multifunctional Ca²⁺/calmodulin-dependent kinase IIδ (CaMKIIδ) regulates arteriogenesis in a mouse model of flow-mediated remodeling.

OBJECTIVE:Sustained hemodynamic stress mediated by high blood flow promotes arteriogenesis, the outward remodeling of existing arteries. Here, we examined whether Ca²⁺/calmodulin-dependent kinase II (CaMKII) regulates arteriogenesis. METHODS AND RESULTS:Ligation of the left common carotid led to an...

Full description

Bibliographic Details
Main Authors: Jason A Scott, Paula J Klutho, Ramzi El Accaoui, Emily Nguyen, Ashlee N Venema, Litao Xie, Shuxia Jiang, Megan Dibbern, Sabrina Scroggins, Anand M Prasad, Elisabeth D Luczak, Melissa K Davis, Weiwei Li, Xiaoqun Guan, Johannes Backs, Annette J Schlueter, Robert M Weiss, Francis J Miller, Mark E Anderson, Isabella M Grumbach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3738514?pdf=render

Internet

http://europepmc.org/articles/PMC3738514?pdf=render

Similar Items