The CD200R1 microglial inhibitory receptor as a therapeutic target in the MPTP model of Parkinson’s disease

The CD200R1 microglial inhibitory receptor as a therapeutic target in the MPTP model of Parkinson’s disease

Abstract Background It is suggested that neuroinflammation, in which activated microglial cells play a relevant role, contributes to the development of Parkinson’s disease (PD). Consequently, the modulation of microglial activation is a potential therapeutic target to be taken into account to act ag...

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Bibliographic Details
Main Authors: Neus Rabaneda-Lombarte, Joan Serratosa, Jordi Bové, Miquel Vila, Josep Saura, Carme Solà
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Neuroinflammation
Subjects:
MPTP
Parkinson’s disease
Glia
Microglia
Immune response
CD200-CD200R1 system
Online Access:https://doi.org/10.1186/s12974-021-02132-z

Internet

https://doi.org/10.1186/s12974-021-02132-z

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