The Evolution of Rag Gene Enhancers and Transcription Factor E and Id Proteins in the Adaptive Immune System

The Evolution of Rag Gene Enhancers and Transcription Factor E and Id Proteins in the Adaptive Immune System

Adaptive immunity relies on the V(D)J DNA recombination of immunoglobulin (<i>Ig</i>) and T cell receptor (<i>TCR</i>) genes, which enables the recognition of highly diverse antigens and the elicitation of antigen-specific immune responses. This process is mediated by recombi...

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Bibliographic Details
Main Authors: Genki Yoshikawa, Kazuko Miyazaki, Hiroyuki Ogata, Masaki Miyazaki
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
adaptive immune system
Rag1/2 gene enhancers
E protein
Id protein
bHLH transcription factors
T and B cell development
Online Access:https://www.mdpi.com/1422-0067/22/11/5888

Internet

https://www.mdpi.com/1422-0067/22/11/5888

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