Deficiency of adiponectin protects against ovariectomy-induced osteoporosis in mice.

Adipokine adiponectin (APN) has been recently reported to play a role in regulating bone mineral density (BMD). To explore the mechanism by which APN affects BMD, we investigated BMD and biomechanical strength properties of the femur and vertebra in sham-operated (Sham) and ovariectomized (OVX) APN...

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Main Authors: Fang Wang, Pei-xia Wang, Xiao-lin Wu, Su-ying Dang, Yan Chen, Ying-yin Ni, Li-hong Gao, Shun-yuan Lu, Ying Kuang, Lei Huang, Jian Fei, Zhu-gang Wang, Xiao-fen Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3699501?pdf=render