Global chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes

Global chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes

Abstract Special AT-rich binding protein-1 (SATB1) integrates higher-order chromatin architecture with gene regulation, thereby regulating multiple signaling pathways. In mammalian cells SATB1 directly interacts with β-catenin and regulates the expression of Wnt targets by binding to their promoters...

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Bibliographic Details
Main Authors: Praveena L. Ramanujam, Sonam Mehrotra, Ram Parikshan Kumar, Shreekant Verma, Girish Deshpande, Rakesh K. Mishra, Sanjeev Galande
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81324-2

Internet

https://doi.org/10.1038/s41598-021-81324-2

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