Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition

Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition

The mitogen-activated protein kinases (MAPKs) superfamily comprises three major signaling pathways: the extracellular signal-regulated protein kinases (ERKs), the c-Jun N-terminal kinases or stress-activated protein kinases (JNKs/SAPKs) and the p38 family of kinases.ERK 1/2 signaling has been implic...

Full description

Bibliographic Details
Main Authors: Francesca R. Fusco, Serenella Anzilotti, Carmela Giampà, Clemente Dato, Daunia Laurenti, Alessandro Leuti, Luca Colucci D'Amato, Lorena Perrone, Giorgio Bernardi, Mariarosa A.B. Melone
Format: Article
Language:English
Published: Elsevier 2012-04-01
Series:Neurobiology of Disease
Subjects:
immunohistochemistry
ERK
rolipram
Huntington's disease
R6/2
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112000356

Internet

http://www.sciencedirect.com/science/article/pii/S0969996112000356

Similar Items