Comparative analysis of ear-hole closure identifies epimorphic regeneration as a discrete trait in mammals

Comparative analysis of ear-hole closure identifies epimorphic regeneration as a discrete trait in mammals

The extent to which mammals and other vertebrates share similar mechanisms of tissue regeneration is unclear. Here, the authors use an ear punch assay in spiny mice, which regenerate fully, to show blastema formation and mesenchymal cell proliferation as cell cycle regulators p21 and p27 remain cyto...

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Bibliographic Details
Main Authors: Thomas R. Gawriluk, Jennifer Simkin, Katherine L. Thompson, Shishir K. Biswas, Zak Clare-Salzler, John M. Kimani, Stephen G. Kiama, Jeramiah J. Smith, Vanessa O. Ezenwa, Ashley W. Seifert
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11164

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https://doi.org/10.1038/ncomms11164

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