Establishment of a Novel In Vitro Model of Endometriosis with Oncogenic <i>KRAS</i> and <i>PIK3CA</i> Mutations for Understanding the Underlying Biology and Molecular Pathogenesis

Establishment of a Novel In Vitro Model of Endometriosis with Oncogenic <i>KRAS</i> and <i>PIK3CA</i> Mutations for Understanding the Underlying Biology and Molecular Pathogenesis

Endometriosis-harboring cancer-associated somatic mutations of <i>PIK3CA</i> and <i>KRAS</i> provides new opportunities for studying the multistep processes responsible for the functional and molecular changes in this disease. We aimed to establish a novel in vitro endometrio...

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Bibliographic Details
Main Authors: Mohammad Mahmud Hossain, Kentaro Nakayama, Kamrunnahar Shanta, Sultana Razia, Masako Ishikawa, Tomoka Ishibashi, Hitomi Yamashita, Seiya Sato, Kouji Iida, Kosuke Kanno, Noriyoshi Ishikawa, Tohru Kiyono, Satoru Kyo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
ovarian endometriosis
epithelial cell line
PIK3CA
KRAS
invasion
migration
Online Access:https://www.mdpi.com/2072-6694/13/13/3174

Internet

https://www.mdpi.com/2072-6694/13/13/3174

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