Erythropoietin ameliorates rat experimental autoimmune neuritis by inducing transforming growth factor-β in macrophages.

Erythropoietin (EPO) is a pleiotropic cytokine originally identified for its role in erythropoiesis. In addition, in various preclinical models EPO exhibited protective activity against tissue injury. There is an urgent need for potent treatments of autoimmune driven disorders of the peripheral nerv...

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Bibliographic Details
Main Authors: Anne K Mausberg, Gerd Meyer Zu Hörste, Thomas Dehmel, Mark Stettner, Helmar C Lehmann, Kazim A Sheikh, Bernd C Kieseier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197078?pdf=render