The Release of Excitatory Amino Acids, Dopamine, and Potassium following Transplantation of Embryonic Mesencephalic Dopaminergic Grafts to the Rat Striatum, and Their Effects on Dopaminergic Neuronal Survival In Vitro

A major limitation to the effectiveness of grafts of fetal ventral mesencephalic tissue for parkinsonism is that about 90–95% of grafted dopaminergic neurones die. In rats, many of the cells are dead within 1 day and most cell death is complete within 1 week. Our previous results suggest that a majo...

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Bibliographic Details
Main Authors: Rike Zietlow, Simon R. Sinclair, Christof J. Schwiening, Stephen B. Dunnett, James W. Fawcett
Format: Article
Language:English
Published: SAGE Publishing 2002-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000002783985396