Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAk): An important allosteric enzyme for amino acids production

Aspartate kinase (AK) is an enzyme which is tightly regulated through feedback control and responsible for the synthesis of 4-phospho-l-aspartate from l-aspartate. This intermediate step is at an important branch point where one path leads to the synthesis of lysine and the other to threonine, methi...

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Bibliographic Details
Main Authors: Babu A. Manjasetty, Mark R. Chance, Stephen K. Burley, Santosh Panjikar, Steven C. Almo
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Biotechnology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X14000228