Synthesis, Gastroprotective Effect and Cytotoxicity of New Amino Acid Diterpene Monoamides and Diamides

Synthesis, Gastroprotective Effect and Cytotoxicity of New Amino Acid Diterpene Monoamides and Diamides

Following our studies on the gastroprotective effect and cytotoxicity of terpene derivatives, new amides were prepared from the diterpene 8(17)-labden-15,19-dioic acid (junicedric acid) and its 8(9)-en isomer with C-protected amino acids (amino acid esters). The new compounds were evaluated for thei...

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Bibliographic Details
Main Authors: Daniel Droguett, Cristina Theoduloz, Francisco Monsalve, Guillermo Schmeda-Hirschmann, Mariano Walter Pertino, Jaime A. Rodriguez
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Molecules
Subjects:
labdane diterpenes
amino acid ester amides
gastroprotective effect
cytotoxicity
Online Access:http://www.mdpi.com/1420-3049/15/10/7378/

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http://www.mdpi.com/1420-3049/15/10/7378/

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