Advanced bioinformatic analysis and pathway prediction of NSCLC cells upon cisplatin resistance

Advanced bioinformatic analysis and pathway prediction of NSCLC cells upon cisplatin resistance

Abstract This study aims to identify pathway involvement in the development of cisplatin (cis-diamminedichloroplatinum (II); CDDP) resistance in A549 lung cancer (LC) cells by utilizing advanced bioinformatics software. We developed CDDP-resistant A549 (A549/DDP) cells through prolonged incubation w...

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Main Authors: A K M Nawshad Hossian, Fatema Tuz Zahra, Sagun Poudel, Camille F. Abshire, Paula Polk, Jone Garai, Jovanny Zabaleta, Constantinos M. Mikelis, George Mattheolabakis
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85930-y

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https://doi.org/10.1038/s41598-021-85930-y

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