LEVERAGING BIOLOGICAL REPLICATES TO IMPROVE ANALYSIS IN CHIP-SEQ EXPERIMENTS

LEVERAGING BIOLOGICAL REPLICATES TO IMPROVE ANALYSIS IN CHIP-SEQ EXPERIMENTS

ChIP-seq experiments identify genome-wide profiles of DNA-binding molecules including transcription factors, enzymes and epigenetic marks. Biological replicates are critical for reliable site discovery and are required for the deposition of data in the ENCODE and modENCODE projects. While early repo...

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Bibliographic Details
Main Authors: Yajie Yang, Justin Fear, Jianhong Hu, Irina Haecker, Lei Zhou, Rolf Renne, David Bloom, Lauren M McIntyre
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
ChIP-seq
peak identification
biological replicates
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014600106

Internet

http://www.sciencedirect.com/science/article/pii/S2001037014600106

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