LEVERAGING BIOLOGICAL REPLICATES TO IMPROVE ANALYSIS IN CHIP-SEQ EXPERIMENTS
ChIP-seq experiments identify genome-wide profiles of DNA-binding molecules including transcription factors, enzymes and epigenetic marks. Biological replicates are critical for reliable site discovery and are required for the deposition of data in the ENCODE and modENCODE projects. While early repo...
Main Authors: | Yajie Yang, Justin Fear, Jianhong Hu, Irina Haecker, Lei Zhou, Rolf Renne, David Bloom, Lauren M McIntyre |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037014600106 |
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