Ferroptosis in Different Pathological Contexts Seen through the Eyes of Mitochondria

Ferroptosis is a recently described form of regulated cell death characterized by intracellular iron accumulation and severe lipid peroxidation due to an impaired cysteine-glutathione-glutathione peroxidase 4 antioxidant defence axis. One of the hallmarks of ferroptosis is a specific morphological p...

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Bibliographic Details
Main Authors: V. Otasevic, M. Vucetic, I. Grigorov, V. Martinovic, A. Stancic
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/5537330