Metabolic control of PPAR activity by aldehyde dehydrogenase regulates invasive cell behavior and predicts survival in hepatocellular and renal clear cell carcinoma

Metabolic control of PPAR activity by aldehyde dehydrogenase regulates invasive cell behavior and predicts survival in hepatocellular and renal clear cell carcinoma

Abstract Background Changes in cellular metabolism are now recognized as potential drivers of cancer development, rather than as secondary consequences of disease. Here, we explore the mechanism by which metabolic changes dependent on aldehyde dehydrogenase impact cancer development. Methods ALDH7A1...

Full description

Bibliographic Details
Main Authors: Diana Andrejeva, Jan-Michael Kugler, Hung Thanh Nguyen, Anders Malmendal, Mette Lind Holm, Birgitte Groenkaer Toft, Anand C. Loya, Stephen M. Cohen
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-5061-7

Internet

http://link.springer.com/article/10.1186/s12885-018-5061-7

Similar Items