Metabolic control of PPAR activity by aldehyde dehydrogenase regulates invasive cell behavior and predicts survival in hepatocellular and renal clear cell carcinoma
Abstract Background Changes in cellular metabolism are now recognized as potential drivers of cancer development, rather than as secondary consequences of disease. Here, we explore the mechanism by which metabolic changes dependent on aldehyde dehydrogenase impact cancer development. Methods ALDH7A1...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | BMC Cancer |
Online Access: | http://link.springer.com/article/10.1186/s12885-018-5061-7 |